Not sure where to begin in order to start using CMIF/MSR? Please refer to this PDF for assistance

... News and Announcements

To Nikon A1R Users:

The software has been updated on Feb. 5, 2021.

To make the software looking as similar as the old version and make sure all functions work properly, please note the new username/password are listed in Nikon A1R room.

Please watch this video (below) for the comparison between the old and new version software (Notice: this is only for the reference purpose, some details are not identical).

(YouTube - Created by University of Pittsburgh Center for Biologic Imaging)

We are working on a new version manual. It will be available to all users soon.

--CMIF, Feb. 9, 2021


On 1/7/2020 our scheduling system (FOM.osu.edu) that is used for making reservations for our instrumentation was integrated into Workday. All users will need to have a Workday requisition that has been entered into FOM.

For directions on how to create a requisition in Workday that will be used in FOM, please refer to this link - https://go.osu.edu/fomrequisition. Please make sure to select "CMIF - Campus Microscopy Imaging Facility" as the supplier.

Imaging Beyond the Diffraction Limit: Nikon N-SIM and N-STORM Super-resolution Systems coming to CMIF/MSR soon

Excuse the disruption as we remodel to house the system in the BRT268 BSL2 suite!

CMIF / OSUCCC MSR Training Policy Update

Training is an Important Mission of the CMIF / OSUCCCMSR!
Not only does it afford trainees the experience hands-on operation of sophisticated and expensive imaging systems but also has many other advantages. Intimate familiarity with our instrumentation allows users to explore aspects of imaging that they might not otherwise have considered and also brings down operating costs, a critical factor in budgeting research budgets. Working closely with experienced CMIF staff also allows trainees and our staff to mutually explore various approaches to experimental design, maximizing the quality and type of data afforded by our imaging systems. And of course generally a user that knows what they are looking for in a specimen according to the experimental design, which to a third party might not be so obvious.

Currently We Are Operating Under an OR approved Phase III Covid SOP
Which unfortunately due to social distancing restrictions, makes one-on-one training challenging. We have submitted a Phase IV SOP for one-on-one training when social distancing is impractical due to finer manipulations of specimens or instrumentation. Our SOP is under review and needs to be aligned with training protocols in the other OSU cores.

Interim Training Procedures
Meanwhile we have alternatives. Our trained staff can operate the instrumentation while the user observes – either at a distance (we have found that there is a surprising amount of co-ordination that can be accomplished by observing our screens at a 6’ distance and verbally communicating with our operating staff) or via zoom where a phone camera is set up to focus on the specimen, operating panel or the screen allowing real time communication between staff operator and the user.

Future Digital Remote Training Options
We are currently purchasing tripods for cell phones to allow such positioning. We are also working on putting together a library of training videos to cover some of the more basic aspects of each instrument. We will continue this effort even when the Covid restrictions are ended since these may replace the more basic one-on-one initial training, thus freeing up time for our staff to work with more users and give them more time to work on experimental design, methods development and equipment proposals.

We understand your frustration but please rest assured we are as keen to get back to training as much as you are! - Paul

New CMIF/MSR Associate Director

We are excited to announce that Dr. Tong Zhang will be joining us as the new Associate Director of the CMIF/MSR. Tong received his BSc in Biochemistry and PhD in Biology from McGill University and was previously Light Microscopy Specialist for the Waitt Advanced Biophotonics Core Facility at the Salk Institute for Biological Studies, La Jolla. Tong brings a wealth of experience with varied light microscopy techniques including super resolution imaging: SIM, STED, PALM/STORM, X-Clarity & Lightsheet; FRET, FRAP and photoswitchable protein imaging; multi-photon imaging; spectral imaging; TIRF; FCS; spinning-disk; Zeiss Airyscan; laser scanning confocal; laser dissecting microscopy; wide-field fluorescence imaging; deconvolution imaging; live-cell imaging; DIC, phase contrast, dark field and bright field imaging. Tong has over 15 years of experience in microscopy and will take a leadership role in the execution of technical and management functions within the CMIF. Tong provides professional trainings to ensure users to accomplish high quality research. He will also provide consultation to users and help researchers to transfer their scientific questions into microscopy solutions. Tong has applied his microscopy knowledge and skills in many fields of studies and published in top tier journals. Tong has won many local and international microscopy competition awards. We welcome Tong onboard in the next couple of months.